Hiromi Hagiwara Selected Research

Gap Junction beta-1 Protein

6/2008	The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma.
8/2007	Enhancing effect of connexin 32 gene on vinorelbine-induced cytotoxicity in A549 lung adenocarcinoma cells.
3/2007	Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cells.
11/2006	Connexin 32 expression reduces malignant phenotype in human A549 adenocarcinoma cells: Implication of Src involvement.
10/2006	Connexin 32 as an anti-invasive and anti-metastatic gene in renal cell carcinoma.
4/2006	Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cells.
4/2005	A Src family inhibitor (PP1) potentiates tumor-suppressive effect of connexin 32 gene in renal cancer cells.
2/2005	Cytotoxic effect of the Her-2/Her-1 inhibitor PKI-166 on renal cancer cells expressing the connexin 32 gene.

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Hiromi Hagiwara Research Topics

Disease

11	Neoplasms (Cancer) 07/2011 - 02/2005
5	Renal Cell Carcinoma (Grawitz Tumor) 06/2008 - 08/2005
4	Heart Failure 02/2022 - 01/2017
3	Lung Neoplasms (Lung Cancer) 03/2021 - 07/2005
3	Kidney Neoplasms (Kidney Cancer) 08/2005 - 02/2005
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 01/2003
2	Acute Coronary Syndrome 01/2021 - 01/2020
2	Osteoporosis 03/2015 - 07/2011
2	Rheumatoid Arthritis 06/2011 - 05/2010
2	Body Weight (Weight, Body) 09/2008 - 08/2004
2	Hypoxia (Hypoxemia) 06/2008 - 04/2006
2	Adenocarcinoma of Lung 08/2007 - 11/2006
1	Human Influenza (Influenza) 02/2022
1	Iron Deficiencies 08/2021
1	Hemorrhage 01/2021
1	Drug-Related Side Effects and Adverse Reactions 01/2020
1	Heart Arrest (Cardiac Arrest) 01/2019
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Male Infertility (Male Sterility) 09/2016
1	Osteopetrosis 03/2015
1	Hyperlipidemias (Hyperlipidemia) 07/2011
1	Arteriosclerosis 07/2011
1	Joint Diseases (Joint Disease) 05/2010
1	Necrosis 05/2010
1	Synovitis 05/2010
1	Neoplasm Metastasis (Metastasis) 06/2008
1	Osteosarcoma (Osteogenic Sarcoma) 08/2007
1	Adenocarcinoma 11/2006
1	Prostatic Neoplasms (Prostate Cancer) 06/2005
1	Bone Resorption 04/2004
1	Gliosis 01/2003
1	Hypertrophy 01/2003
1	Stroke (Strokes) 01/2003

Drug/Important Bio-Agent (IBA)

8	Gap Junction beta-1 ProteinIBA 06/2008 - 02/2005
7	ConnexinsIBA 06/2008 - 02/2005
3	Proteins (Proteins, Gene)FDA Link 09/2016 - 04/2006
2	Clopidogrel (Plavix)FDA Link 01/2021 - 01/2020
2	Prasugrel Hydrochloride FDA Link 01/2021 - 01/2020
2	PolyphenolsIBA 03/2015 - 07/2011
2	Dihydrotachysterol (AT 10)IBA 09/2008 - 08/2004
2	Connexin 43 (Connexin43)IBA 08/2007 - 07/2006
2	Plasminogen Activator Inhibitor 1IBA 04/2006 - 01/2003
2	Endothelins (Endothelin)IBA 01/2003 - 01/2003
1	Influenza Vaccines (Influenza Vaccine)FDA Link 02/2022
1	Insulin (Novolin)FDA Link 01/2022
1	Sodium-Glucose Transport ProteinsIBA 12/2021
1	IronIBA 08/2021
1	MicroRNAs (MicroRNA)IBA 03/2021
1	ApigeninIBA 03/2021
1	Nitroglycerin (Dynamite)FDA LinkGeneric 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Nicardipine (Dagan)FDA LinkGeneric 01/2019
1	Isosorbide Dinitrate (Isordil)FDA LinkGeneric 01/2019
1	DiureticsIBA 01/2017
1	Antihypertensive Agents (Antihypertensives)IBA 01/2017
1	3,4-dihydroxyphenylethanol (hydroxytyrosol)IBA 07/2011
1	oleuropeinIBA 07/2011
1	tocilizumab (atlizumab)FDA Link 06/2011
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 06/2011
1	Interleukin-6 (Interleukin 6)IBA 06/2011
1	Infliximab (Remicade)FDA Link 05/2010
1	C-Reactive ProteinIBA 05/2010
1	Protease Inhibitors (Protease Inhibitor)IBA 08/2007
1	Vinorelbine (Navelbine)FDA LinkGeneric 08/2007
1	Vinblastine (Vinblastine Sulfate)FDA Link 03/2007
1	Urokinase Plasminogen Activator ReceptorsIBA 04/2006
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 04/2006
1	Messenger RNA (mRNA)IBA 04/2006
1	src-Family KinasesIBA 08/2005
1	Phosphotransferases (Kinase)IBA 08/2005
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2005
1	PPAR deltaIBA 07/2005
1	ProstaglandinsIBA 07/2005
1	4- (3- (2- propyl- 3- hydroxy- 4- acetyl)phenoxy)propyloxyphenoxy acetic acidIBA 07/2005
1	LigandsIBA 06/2005
1	PKI 166IBA 02/2005
1	tributyltinIBA 08/2004
1	mono-n-butyltinIBA 08/2004
1	QuercetinIBA 04/2004
1	Endothelin B ReceptorIBA 01/2003
1	Bosentan (Tracleer)FDA Link 01/2003
1	Endothelin A ReceptorIBA 01/2003
1	Endothelin Receptors (Endothelin Receptor)IBA 01/2003

Therapy/Procedure

4	Therapeutics 08/2021 - 10/2006
2	Percutaneous Coronary Intervention 01/2021 - 01/2020
1	Aftercare (After-Treatment) 05/2010
1	Drug Therapy (Chemotherapy) 03/2007